The deleterious effects of exogenous angiotension I and angiotensin II on myocardial ischemia-reperfusion injury.
نویسندگان
چکیده
منابع مشابه
Effect of Losartan injection into paraventricular nucleus on the deleterious effects of angiotensin II in renal ischemia-reperfusion injury
Introduction: The aim of this study was to investigate the effect of angiotensin II (Ang II) and losartan injections into paraventricular nucleus (PVN) on renal ischemia-reperfusion injury. Methods: After right nephrectomy in male rats, a cannula was inserted into the right PVN. One week later, renal ischemia-reperfusion (IR) injury was induced by clamping the left renal artery for 45 min, a...
متن کاملEffect of Losartan injection into paraventricular nucleus on the deleterious effects of angiotensin II in renal ischemia-reperfusion injury
Introduction: The aim of this study was to investigate the effect of angiotensin II (Ang II) and losartan injections into paraventricular nucleus (PVN) on renal ischemia-reperfusion injury. Methods: After right nephrectomy in male rats, a cannula was inserted into the right PVN. One week later, renal ischemia-reperfusion (IR) injury was induced by clamping the left renal artery for 45 min, and ...
متن کاملProtective effects of tanshinone IIA sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
Objective(s): This study investigated the protective effect of tanshinone IIA sodium sulfonate (TSS) on ischemia-reperfusion (I/R) induced cardiac injury, and the underlying mechanism of action. Materials and Methods:Male Sprague-Dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. Half an hour before the left coronary artery ligation, rats were ...
متن کاملMyocardial protection from ischemia/reperfusion injury by exogenous galanin fragment
BACKGROUND AND PURPOSE Galanin is a multifunctional neuropeptide with pleiotropic roles. The present study was designed to evaluate the potential effects of galanin (2-11) (G1) on functional and metabolic abnormalities in response to myocardial ischemia-reperfusion (I/R) injury. EXPERIMENTAL APPROACH Peptide G1 was synthesized by the 9-fluorenylmethoxycarbonyl (Fmoc)-based solid-phase method....
متن کاملBlockade of Central Angiotensin II AT1 Receptor Protects the Brain from Ischemia/Reperfusion Injury in Normotensive Rats
Background: Stroke is the third leading cause of invalidism and death in industrialized countries. There are conflicting reports about the effects of Angiotensin II on ischemia-reperfusion brain injuries and most data have come from chronic hypertensive rats. In this study, hypotensive and non-hypotensive doses of candesartan were used to investigate the effects of angiotensin II AT1 receptor b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1994
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.58.362